The 49ers have been hit hard by injuries this season, losing Christian McCaffrey, Jake Moody and now an All-Pro defender.

With former Michigan kicker Jake Moody sidelined with an ankle injury, the San Francisco 49ers have reportedly found a ...

Take a look at the odds entering the Week 6 schedule for every NFL team to play in Super Bowl LIX, scheduled for Sunday, Feb.

San Francisco 49ers head coach Kyle Shanahan, quarterback Brock Purdy, and defensive coordinator Nick Sorensen spoke to ...

An NFL exec took shots at teams like the Dallas Cowboys and San Francisco 49ers for recent contracts they gave to their top ...

The San Francisco 49ers are struggling to find their footing after a disappointing 2-3 start to the season, having lost three ...

Two weeks after faltering on the road to the Los Angeles Rams, the 49ers blew another 10-point lead and exited with a 24-23 ...

NFL Week 6 odds, picks, predictions, TV, streaming information for Thursday Night Football game between San Francisco 49ers ...

We’re now five weeks into the NFL season, and there are far more questions than answers for the San Francisco 49ers.

Despite Lenoir’s huge play, the 49ers’ suffered an offensive collapse in the second half, turning the ball over three times.

The San Fransisco 49ers (2-3) and Seattle Seahawks (3-2) meet Thursday at Lumen Field. Kickoff is scheduled for 8:15 p.m. ET ...

The 49ers are a 7.5-point favorite over the Cardinals in NFL Week 5 odds for the game, courtesy of BetMGM Sportsbook. San ...