No writing assistance was utilized in the production of this manuscript. Homozygous familial hypercholesterolemia is a rare but significant cause of early-onset coronary heart disease. Early ...

Familial hypercholesterolemia results from gene mutations approximately halving the number of functional LDL receptors in heterozygotes and a greater lack in homozygotes. Reduced receptor-mediated ...

Familial hypercholesterolemia (FH) is an inherited condition consisting of lifelong elevated LDL cholesterol levels and increased risk of cardiovascular disease. Among Western populations, the ...