Researchers investigate chromatin conformational and epigenomic reorganization during the development of the prefrontal ...

Researchers used single-cell and spatial genomics to map cell-type-specific changes in the middle temporal gyrus, identifying distinct disease phases in Alzheimer’s progression.

Researchers suggest findings could help to pinpoint cell types most vulnerable to conditions such as schizophrenia, and ...

A new study has created a map of DNA modification in two regions of the brain critical to learning, memory and emotional regulation. The map offers a benchmark for ensuring stem cell-based models ...

Researchers have created a map of DNA modification in two regions of the brain critical to learning, memory and emotional ...

This work presents a valuable finding on how the interplay between transcription factors SOX2 and OCT4 establishes the pluripotency network in early mouse embryos. Despite the high quality of the data ...

Alonso/UCSFFluorescent image of a developing human hippocampus. Key takeawaysA UCLA-led study has created a map of DNA ...

Chromatin is a flexibly joined chain of nucleosomes that exists inside the nucleus of eukaryotic cells and has been described as a 'bead on a string'. Chromatin organization strengthens DNA for ...

Watching dividing cells filmed with time-lapse microcinematography, he remarked, was to be amazed by the ferocity of continuous movement of the chromatin. One should remember, he said, that the ...