Kyler Murray reached a top speed of 21.27 mph on his 50-yard TD run, the fastest speed by a quarterback as a ball carrier over the last 8 seasons. #AZvsSF | @AZCardinals pic.twitter.com/K9vTkOKURA

After Arizona's defense forced a three-and-out, the Cardinals received possession. After finding tight end Trey McBride on a 22-yard gain, Murray kept the ball on a quarterback keeper and went untouched on a 50-yard run to the end zone.

Arizona Cardinals quarterback Kyler Murray broke free for a 50-yard touchdown run on the team's second play of the game